GCDH encodes for the enzyme catalyzing the sixth step of the lysine degradation pathway.Autosomal recessive variants in GCDH are associated with glutaric aciduria type I (GA1), of which a wide genotypic spectrum of pathogenic variants have been described.In Glass Defrost Element this study, hiPSC lines derived from four GA1 patients with different
Tetanus with Low back and Knee Pain, Abdominal Distension and Constipation as Initial Presentations: Report of a Deaf and Mute Case and Literature Review
Tetanus is a life-threatening and fatal disease that can be prevented by vaccination.The diagnosis of tetanus is based solely on medical history and clinical symptoms and is very prone to misdiagnosis, undertreatment, and delayed treatment.We reported a deaf and mute patient with tetanus with low back pain, bilateral knee pain, and abdominal disten
Occurrence of Escherichia coli virulence genes in feces of wild birds from Central Italy
Objective: To investigate the potential role of wild birds as fecal spreaders of enteropathogenic, enterohemorrhagic and Shiga-toxins producing Escherichia coli (E.coli), enteropathogenic E.coli, enterohemorrhagic E.coli and Shiga toxin-producing E.coli strains.Methods: Fecal samples collected from 121 wild birds of different orders and species wer
Sparse neural network optimization by Simulated Annealing
The over-parameterization of neural networks and the local optimality of backpropagation algorithm have been two major problems associated with deep-learning.In order to reduce the redundancy of neural network parameters, the conventional approach has been to prune branches with small weights.However, this only solves the problem of parameter redun
Performance Analysis of Wireless Energy Harvesting Multihop Cluster-Based Networks Over Nakagami- ${m}$ Fading Channels
This paper studies the performance analysis of wireless energy harvesting (EH) cluster-based multi-hop 533 networks, where all communication nodes harvest energy from the radiated signals transmitted by multiple power beacons (PBs) to support the information transmission.To this end, we propose three relay selection schemes.The first scheme tries t